Whole-Brain Functional Network Connectivity Abnormalities in Affective and Non-Affective Early Phase Psychosis.

ABSTRACT: Psychosis disorders share overlapping symptoms and are characterized by a wide-spread breakdown in functional brain integration. Although neuroimaging studies have identified numerous connectivity abnormalities in affective and non-affective psychoses, whether they have specific or unique connectivity abnormalities, especially within the early stage is still poorly understood. The early phase of psychosis is a critical period with fewer chronic confounds and when treatment intervention may be most effective. In this work, we examined whole-brain functional network connectivity (FNC) from both static and dynamic perspectives in patients with affective psychosis (PAP) or with non-affective psychosis (PnAP) and healthy controls (HCs). A fully automated independent component analysis (ICA) pip

SUBMITTER: Fu Z 

PROVIDER: S-EPMC8250435 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature