Severe mental illness is associated with increased mortality and severe course of COVID-19.

ABSTRACT:

Objective

Psychiatric disorders have been associated with unfavourable outcome following respiratory infections. Whether this also applies to coronavirus disease 2019 (COVID-19) has been scarcely investigated.

Methods

Using the Danish administrative databases, we identified all patients with a positive real-time reverse transcription-polymerase chain reaction test for COVID-19 in Denmark up to and including 2 January 2021. Multivariable cox regression was used to calculate 30-day absolute risk and average risk ratio (ARR) for the composite end point of death from any cause and severe COVID-19 associated with psychiatric disorders, defined using both hospital diagnoses and redemption of psychotropic drugs.

Results

We included 144,321 patients with COVID-19. Compared wi

SUBMITTER: Barcella CA 

PROVIDER: S-EPMC8250986 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature