Ultraviolet A radiation and COVID-19 deaths in the USA with replication studies in England and Italy.

ABSTRACT:

Background

Understanding factors impacting deaths from COVID-19 is of the highest priority. Seasonal variation in environmental meteorological conditions affects the incidence of many infectious diseases and may also affect COVID-19. Ultraviolet (UV) A (UVA) radiation induces release of cutaneous photolabile nitric oxide (NO) impacting the cardiovascular system and metabolic syndrome, both COVID-19 risk factors. NO also inhibits the replication of SARS-CoV2.

Objectives

To investigate the relationship between ambient UVA radiation and COVID-19 deaths.

Methods

COVID-19 deaths at the county level, across the USA, were modelled in a zero-inflated negative-binomial model with a random effect for states adjusting for confounding by demographic, socioeconomic and long-term e

SUBMITTER: Cherrie M 

PROVIDER: S-EPMC8251104 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature