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Introduction to molecular replacement: a time perspective.


ABSTRACT: This article provides an introduction to the crystal phasing technique known as molecular replacement. The available software is reviewed, and the prospects for future developments are considered. Several examples are described in detail to illustrate potential problems. A brief account of past progress is included. The basic crystallographic equations underlying the procedures are given in an appendix.

SUBMITTER: Dodson E 

PROVIDER: S-EPMC8251348 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature

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Introduction to molecular replacement: a time perspective.

Dodson Eleanor E  

Acta crystallographica. Section D, Structural biology 20210618 Pt 7


This article provides an introduction to the crystal phasing technique known as molecular replacement. The available software is reviewed, and the prospects for future developments are considered. Several examples are described in detail to illustrate potential problems. A brief account of past progress is included. The basic crystallographic equations underlying the procedures are given in an appendix. ...[more]

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