SARS-CoV-2 biology and variants: anticipation of viral evolution and what needs to be done.

ABSTRACT: The global propagation of SARS-CoV-2 and the detection of a large number of variants, some of which have replaced the original clade to become dominant, underscores the fact that the virus is actively exploring its evolutionary space. The longer high levels of viral multiplication occur - permitted by high levels of transmission -, the more the virus can adapt to the human host and find ways to success. The third wave of the COVID-19 pandemic is starting in different parts of the world, emphasizing that transmission containment measures that are being imposed are not adequate. Part of the consideration in determining containment measures is the rationale that vaccination will soon stop transmission and allow a return to normality. However, vaccines themselves represent a selection pressure

SUBMITTER: Luo R 

PROVIDER: S-EPMC8251359 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature