Dementia increases mortality beyond effects of comorbid conditions: A national registry-based cohort study.

ABSTRACT:

Background and purpose

Mortality is known to be markedly increased in people with dementia. However, the association between multiple chronic conditions and mortality in dementia is not well clarified. The aim of this study was to investigate the impact of somatic and psychiatric diseases on mortality in dementia compared with the general elderly population.

Methods

Using a cohort study design, nationwide registry data from 2006 to 2015 on dementia and psychiatric and somatic comorbidities defined by the Charlson Comorbidity Index (CCI) were linked. Impact of chronic conditions was assessed according to mortality rate ratios (MRRs) in all Danish residents aged ≥65 years with and without dementia.

Results

Our population comprised 1,518,917 people, of whom 114,109 peopl

SUBMITTER: Taudorf L 

PROVIDER: S-EPMC8251545 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature