Maternal iron status during early pregnancy and school-age, lung function, asthma, and allergy: The Generation R Study.

ABSTRACT:

Background

Iron deficiency during early life could affect the developing lung and immune system, and influence child's respiratory or allergy outcomes in later life.

Objective

To examine the associations of maternal iron status during early pregnancy with child's lung function, asthma, inhalant allergic sensitization, and physician-diagnosed inhalant allergy at school-age.

Methods

In a population-based cohort study, among 3825 mother-child pairs, ferritin, transferrin concentrations, and transferrin saturation were measured from maternal venous blood samples during early pregnancy. In children at the age of 10 years, spirometry was used to determine child's lung function, current asthma and physician-diagnosed inhalant allergy were assessed by questionnaires, and inha

SUBMITTER: Quezada-Pinedo HG 

PROVIDER: S-EPMC8251584 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature