Chronic opioid use and complication risks in women with endometriosis: A cohort study in US administrative claims.

ABSTRACT:

Background

Women with endometriosis are prescribed opioids for pain relief but may be vulnerable to chronic opioid use given their comorbidity profile.

Methods

A cohort study was conducted in the Clinformatics™ DataMart database between 2006 and 2017 comparing women aged 18-50 years with endometriosis (N = 36 373) to those without (N = 2 172 936) in terms of risk of chronic opioid use, opioid dependence diagnosis, and opioid overdose. Chronic opioid use was defined as ≥120 days' supply dispensed or ≥10 fills of an opioid during any 365-day interval. Among women with endometriosis, we evaluated factors associated with higher risk of chronic opioid use and quantified the risk of complications associated with the use of opioids.

Results

Women with endometriosis were at g

SUBMITTER: Chiuve SE 

PROVIDER: S-EPMC8251707 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature