Active surveillance of metastatic renal cell carcinoma: Results from a prospective observational study (MaRCC).

ABSTRACT:

Background

Systemic therapy (ST) can be deferred in patients who have metastatic renal cell carcinoma (mRCC) and slow-growing metastases. Currently, this subset of patients managed with active surveillance (AS) is not well described in the literature.

Methods

This was a prospective observational study of patients with mRCC across 46 US community and academic centers. The objective was to describe baseline characteristics and demographics of patients with mRCC initially managed by AS, reasons for AS, and patient outcomes. Descriptive statistics were used to characterize demographics, baseline characteristics, and patient-related outcomes. Wilcoxon 2-sample rank-sum tests and χ² tests were used to assess differences between ST and AS cohorts in continuous and catego

SUBMITTER: Harrison MR 

PROVIDER: S-EPMC8251950 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature