Free-breathing simultaneous T1 , T2 , and T2∗ quantification in the myocardium.

ABSTRACT:

Purpose

To implement a free-breathing sequence for simultaneous quantification of T1 , T2 , and T2∗ for comprehensive tissue characterization of the myocardium in a single scan using a multi-gradient-echo readout with saturation and T2 preparation pulses.

Methods

In the proposed Saturation And T2 -prepared Relaxometry with Navigator-gating (SATURN) technique, a series of multi-gradient-echo (GRE) images with different magnetization preparations was acquired during free breathing. A total of 35 images were acquired in 26.5 ± 14.9 seconds using multiple saturation times and T2 preparation durations and with imaging at 5 echo times. Bloch simulations and phantom experiments were used to validate a 5-parameter fit model for accurate relaxometry. Free-breathing simultaneous T1 ,

SUBMITTER: Hermann I 

PROVIDER: S-EPMC8252099 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature