Association between nasal and nasopharyngeal bacterial colonization in early life and eczema phenotypes.

ABSTRACT:

Background

An association has been reported between early life Staphylococcus aureus nasal carriage and higher risk of childhood eczema, but it is unclear whether this relationship is causal and associations with other bacterial species are unclear.

Objective

To examine the associations of early life nasal and nasopharyngeal bacterial carriage with eczema phenotypes, and the direction of any associations identified.

Methods

Among 996 subjects of a population-based prospective cohort study, nasal swabs for Staphylococcus  aureus, and nasopharyngeal swabs for Streptococcus pneumoniae, Moraxella catarrhalis and Haemophilus influenzae were collected and cultured from age 6 weeks to 6 years. Never, early, mid-, late transient and persistent eczema phenotypes were identifie

SUBMITTER: Hu C 

PROVIDER: S-EPMC8252109 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature