Longitudinal change in lung function and subsequent risks of cardiovascular events: evidence from four prospective cohort studies.

ABSTRACT:

Background

Lung function is constantly changing over the life course. Although the relation of cross-sectional lung function measure and adverse outcomes has been reported, data on longitudinal change and subsequent cardiovascular (CV) events risks are scarce. Therefore, this study is to determine the association of longitudinal change in lung function and subsequent cardiovascular risks.

Methods

This study analyzed the data from four prospective cohorts. Subjects with at least two lung function tests were included. We calculated the rate of forced respiratory volume in 1 s (FEV1) and forced vital capacity (FVC) decline for each subject and categorized them into quartiles. The primary outcome was CV events, defined as a composite of coronary heart disease (CHD), chronic hear

SUBMITTER: Cheng YJ 

PROVIDER: S-EPMC8252272 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature