Effect of Salvage Radiotherapy and Endocrine Therapy on Patients with Biochemical Recurrence After Prostate Cancer Operation- a Meta‑Analysis.

ABSTRACT:

Context

Several studies reported the application of androgen deprivation therapy and radiotherapy in patients with biochemical recurrence after prostate cancer operation.

Objective

To perform a systematic review and meta-analysis evaluating of endocrine therapy and radiotherapy in patients with biochemical recurrence after prostate cancer surgery. The primary end point was biochemical progression-free survival (bPFS). Secondary end point was overall survival (OS).

Methods

A systematic review of PubMed/Medline, Embase, and Cochrane databases to identify relevant studies published in English up to March 2020. Twelve studies were selected for inclusion.

Results

There were 11 studies included in the present study. Including two randomized controlled trials and nine

SUBMITTER: Yuan Y 

PROVIDER: S-EPMC8252357 | biostudies-literature | 2021 May-Jun

REPOSITORIES: biostudies-literature