Detection of cancers and advanced adenomas in asymptomatic participants in colorectal cancer screening: a cross-sectional study.

ABSTRACT:

Objectives

To assess detection rates for colorectal cancer (CRC) and advanced adenomas in asymptomatic CRC screening participants and bowel symptoms in association with CRC and advanced adenoma.

Design

Cross-sectional study.

Setting

Two screening centres.

Participants

42 554 men and women, aged 50-74 years, participating in a randomised CRC screening trial. 36 059 participants underwent a sigmoidoscopy (and follow-up colonoscopy if positive sigmoidoscopy) and 6495 underwent a colonoscopy after a positive faecal immunochemical test (FIT).

Primary and secondary outcome measures

Proportion of asymptomatic participants diagnosed with CRC or advanced adenomas. Prevalence of bowel symptoms (rectal bleeding, change in bowel habits, diarrhoea, constipation, bloa

SUBMITTER: Schult AL 

PROVIDER: S-EPMC8252874 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature