Predictors of Time-in-Range (70-180 mg/dL) Achieved Using a Closed-Loop Control System.

ABSTRACT: Background: Studies of closed-loop control (CLC) in patients with type 1 diabetes (T1D) consistently demonstrate improvements in glycemic control as measured by increased time-in-range (TIR) 70-180 mg/dL. However, clinical predictors of TIR in users of CLC systems are needed. Materials and Methods: We analyzed data from 100 children aged 6-13 years with T1D using the Tandem Control-IQ CLC system during a randomized trial or subsequent extension phase. Continuous glucose monitor data were collected at baseline and during 12-16 weeks of CLC use. Participants were stratified into quartiles of TIR on CLC to compare clinical characteristics. Results: TIR for those in the first, second, third, and fourth quartiles was 54%, 65%, 71%, and 78%, respectively

SUBMITTER: Schoelwer MJ 

PROVIDER: S-EPMC8252894 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature