Energy Status Differentially Modifies Feeding Behavior and POMC^ARC Neuron Activity After Acute Treadmill Exercise in Untrained Mice.

ABSTRACT: Emerging evidence identifies a potent role for aerobic exercise to modulate activity of neurons involved in regulating appetite; however, these studies produce conflicting results. These discrepancies may be, in part, due to methodological differences, including differences in exercise intensity and pre-exercise energy status. Consequently, the current study utilized a translational, well-controlled, within-subject, treadmill exercise protocol to investigate the differential effects of energy status and exercise intensity on post-exercise feeding behavior and appetite-controlling neurons in the hypothalamus. Mature, untrained male mice were exposed to acute sedentary, low (10m/min), moderate (14m/min), and high (18m/min) intensity treadmill exercise in a randomized crossover design. Fed an

SUBMITTER: Landry T 

PROVIDER: S-EPMC8253227 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature