Does chronic oral anticoagulation reduce in-hospital mortality among COVID-19 older patients?

ABSTRACT:

Background

Patients hospitalized with COVID-19 experienced an increased risk of venous thromboembolism.

Aims

To evaluate the effect of chronic oral anticoagulation (OAC) therapy, both with vitamin K antagonists (VKAs) or direct oral anticoagulants (DOACs), on prognosis of COVID-19 older patients.

Methods

Single-center prospective study conducted in the Emergency Department (ED) of a teaching hospital, referral center for COVID-19 in central Italy. We evaluated all the patients ≥ 65 years, consecutively admitted to our ED for confirmed COVID-19. We compared the clinical outcome of those who were on chronic OAC at ED admission with those who did not, using a propensity score matched paired cohort of controls. The primary study endpoint was all-cause in-hospital death. P

SUBMITTER: Covino M 

PROVIDER: S-EPMC8254066 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature