Therapeutic effect of prolonged testosterone pretreatment in women with poor ovarian response: A randomized control trial.

ABSTRACT:

Purpose

This study compared the therapeutic effects of transdermal testosterone gel (TTG) application at 4 and 6 weeks before controlled ovarian hyperstimulation (COH) in women with poor ovarian response (POR).

Methods

In this randomized control trial, infertile women with POR who underwent in vitro fertilization (IVF) were recruited and randomly classified into 4 week (n = 42) and 6 week (n = 38) TTG treatment groups and control group (n = 42). The primary outcome was total number of retrieved mature oocytes. The secondary outcomes were the biochemical pregnancy rate, clinical pregnancy rate, and ongoing pregnancy rate.

Results

No significant differences were observed in the number of oocytes retrieved, mature oocytes and embryos between all groups. Human chorionic g

SUBMITTER: Hoang QH 

PROVIDER: S-EPMC8254170 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature