Factors affecting accuracy and precision in ultrasound guided radiotherapy.

ABSTRACT:

Background and purpose

Transperineal ultrasound (TPUS) is used clinically for directly assessing prostate motion. Factors affecting accuracy and precision in TPUS motion estimation must be assessed to realise its full potential.

Methods and materials

Patients were imaged using volumetric TPUS during the Clarity-Pro trial (NCT02388308). Prostate motion was measured online at patient set-up and offline by experienced observers. Cone beam CT with markers was used as a comparator and observer performance was also quantified. The influence of different clinical factors was examined to establish specific recommendations towards efficacious ultrasound guided radiotherapy.

Results

From 330 fractions in 22 patients, offline observer random errors were 1.5 mm, 1.3 mm, 1.9 mm (l

SUBMITTER: Grimwood A 

PROVIDER: S-EPMC8254201 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature