The predicting roles of carcinoembryonic antigen and its underlying mechanism in the progression of coronavirus disease 2019.

ABSTRACT:

Background

The coronavirus disease 2019 (COVID-19) has induced a worldwide epidemiological event with a high infectivity and mortality. However, the predicting biomarkers and their potential mechanism in the progression of COVID-19 are not well known.

Objective

The aim of this study is to identify the candidate predictors of COVID-19 and investigate their underlying mechanism.

Methods

The retrospective study was conducted to identify the potential laboratory indicators with prognostic values of COVID-19 disease. Then, the prognostic nomogram was constructed to predict the overall survival of COVID-19 patients. Additionally, the scRNA-seq data of BALF and PBMCs from COVID-19 patients were downloaded to investigate the underlying mechanism of the most important prognost

SUBMITTER: Huang R 

PROVIDER: S-EPMC8254455 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature