Antimicrobial guidelines in clinical practice: incorporating the ethical perspective.

ABSTRACT:

Introduction

Guidelines on antimicrobial therapy are subject to periodic revision to anticipate changes in the epidemiology of antimicrobial resistance and new scientific knowledge. Changing a policy to a broader spectrum has important consequences on both the individual patient level (e.g. effectiveness, toxicity) and population level (e.g. emerging resistance, costs). By combining both clinical data evaluation and an ethical analysis, we aim to propose a comprehensive framework to guide antibiotic policy dilemmas.

Methods

A preliminary framework for decision-making on antimicrobial policy was constructed based on existing literature and panel discussions. Antibiotic policy themes were translated into specific elements that were fitted into this framework. The adapted frame

SUBMITTER: Lambregts M 

PROVIDER: S-EPMC8254525 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature