A major QTL at the LHCGR/FSHR locus for multiple birth in Holstein cattle.

ABSTRACT:

Background

Twin and multiple births are rare in cattle and have a negative impact on the performance and health of cows and calves. Therefore, selection against multiple birth would be desirable in dairy cattle breeds such as Holstein. We applied different methods to decipher the genetic architecture of this trait using de-regressed breeding values for maternal multiple birth of ~ 2500 Holstein individuals to perform genome-wide association analyses using ~ 600 K imputed single nucleotide polymorphisms (SNPs).

Results

In the population studied, we found no significant genetic trend over time of the estimated breeding values for multiple birth, which indicates that this trait has not been selected for in the past. In addition to several suggestive non-significant quantitative

SUBMITTER: Widmer S 

PROVIDER: S-EPMC8255007 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature