Multiparametric MRI for Characterization of the Basal Ganglia and the Midbrain.

ABSTRACT: Objectives To characterize subcortical nuclei by multi-parametric quantitative magnetic resonance imaging. Materials and Methods: The following quantitative multiparametric MR data of five healthy volunteers were acquired on a 7T MRI system: 3D gradient echo (GRE) data for the calculation of quantitative susceptibility maps (QSM), GRE sequences with and without off-resonant magnetic transfer pulse for magnetization transfer ratio (MTR) calculation, a magnetization-prepared 2 rapid acquisition gradient echo sequence for T₁ mapping, and (after a coil change) a density-adapted 3D radial pulse sequence for ²³Na imaging. First, all data were co-registered to the GRE data, volumes of interest (VOIs) for 21 subcortical structures were drawn manually for each vo

SUBMITTER: Schneider TM 

PROVIDER: S-EPMC8255625 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature