β-Carotene prevents weaning-induced intestinal inflammation by modulating gut microbiota in piglets.

ABSTRACT:

Objective

Weaning is an important stage in the life of young mammals, which is associated with intestinal inflammation, gut microbiota disorders, and even death. β-Carotene displays anti-inflammatory and antioxidant activities, which can prevent the development of inflammatory diseases. However, whether β-carotene can affect intestinal microbiota remains unclear.

Methods

Twenty-four piglets were distributed into four groups: the normal suckling group (Con), the weaning group (WG), the weaning+β-carotene (40 mg/kg) group (LCBC), and the weaning+β-carotene (80 mg/kg) group (HCBC). The serum, jejunum, colon, and faeces were collected separately from each group. The effects of β-carotene on the phenotype, overall structure, and composition of gut microbiota were assessed in wean

SUBMITTER: Li R 

PROVIDER: S-EPMC8255870 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature