¹⁷O MAS NMR Correlation Spectroscopy at High Magnetic Fields.

ABSTRACT: The structure of two protected amino acids, FMOC-l-leucine and FMOC-l-valine, and a dipeptide, N-acetyl-l-valyl-l-leucine (N-Ac-VL), were studied via one- and two-dimensional solid-state nuclear magnetic resonance (NMR) spectroscopy. Utilizing ¹⁷O magic-angle spinning (MAS) NMR at multiple magnetic fields (17.6-35.2 T/750-1500 MHz for ¹H) the ¹⁷O quadrupolar and chemical shift parameters were determined for the two oxygen sites of each FMOC-protected amino acids and the three distinct oxygen environments of the dipeptide. The one- and two-dimensional, ¹⁷O, ¹⁵N-¹⁷O, ¹³C-¹⁷O, and ¹H-¹⁷O double-resonance correlation experiments performed on the uniformly ¹³C,¹⁵N

SUBMITTER: Keeler EG 

PROVIDER: S-EPMC8256432 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature