Sex and age differences in isolated traumatic brain injury: a retrospective observational study.

ABSTRACT:

Background

Among the many factors that may influence traumatic brain injury (TBI) progression, sex is one of the most controversial. The objective of this study was to investigate sex differences in TBI-associated morbidity and mortality using data from the largest trauma registry in Japan.

Methods

This retrospective, population-based observational study included patients with isolated TBI, who were registered in a nationwide database between 2004 and 2018. We excluded patients with extracranial injury (Abbreviated Injury Scale score ≥ 3) and removed potential confounding factors, such as non-neurological causes of mortality. Patients were stratified by age and mortality and post-injury complications were compared between males and females.

Results

A total of 51,726 p

SUBMITTER: Hosomi S 

PROVIDER: S-EPMC8256599 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature