Influenza in Malaysian adult patients hospitalized with community-acquired pneumonia, acute exacerbation of chronic obstructive pulmonary disease or asthma: a multicenter, active surveillance study.

ABSTRACT:

Background

Available data on influenza burden across Southeast Asia are largely limited to pediatric populations, with inconsistent findings.

Methods

We conducted a multicenter, hospital-based active surveillance study of adults in Malaysia with community-acquired pneumonia (CAP), acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and acute exacerbation of asthma (AEBA), who had influenza-like illness ≤10 days before hospitalization. We estimated the rate of laboratory-confirmed influenza and associated complications over 13 months (July 2018-August 2019) and described the distribution of causative influenza strains. We evaluated predictors of laboratory-confirmed influenza and severe clinical outcomes using multivariate analysis.

Results

Of 1106 inc

SUBMITTER: Pang YK 

PROVIDER: S-EPMC8256617 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature