Cost-effectiveness of single-layer versus double-layer uterine closure during caesarean section on postmenstrual spotting: economic evaluation alongside a randomised controlled trial.

ABSTRACT:

Objective

To evaluate the cost-effectiveness of double-layer compared with single-layer uterine closure after a first caesarean section (CS) from a societal and healthcare perspective.

Design

Economic evaluation alongside a multicentre, double-blind, randomised controlled trial.

Setting

32 hospitals in the Netherlands, 2016-2018.

Participants

2292 women ≥18 years undergoing a first CS were randomly assigned (1:1). Exclusion criteria were: inability for counselling, previous uterine surgery, known menstrual disorder, placenta increta or percreta, pregnant with three or more fetuses. 1144 women were assigned to single-layer and 1148 to double-layer closure. We included 1620 women with a menstrual cycle in the main analysis.

Interventions

Single-layer unloc

SUBMITTER: Stegwee SI 

PROVIDER: S-EPMC8256741 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature