A scaffolded approach to unearth potential antibacterial components from epicarp of Malaysian Nephelium lappaceum L.

ABSTRACT: The emergence and spread of antimicrobial resistance have been of serious concern to human health and the management of bacterial infectious diseases. Effective treatment of these diseases requires the development of novel therapeutics, preferably free of side effects. In this regard, natural products are frequently conceived to be potential alternative sources for novel antibacterial compounds. Herein, we have evaluated the antibacterial activity of the epicarp extracts of the Malaysian cultivar of yellow rambutan fruit (Nephelium lappaceum L.) against six pathogens namely, Bacillus subtilis, methicillin-resistant Staphylococcus aureus (MRSA), Streptococcus pyogenes, Pseudomonas aeruginosa, Klebsiella pneumoniae and Salmonella enterica. Among a series of solvent extracts, fractions of eth

SUBMITTER: Asghar A 

PROVIDER: S-EPMC8257635 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature