Locating hyperfunctioning parathyroid glands using ¹¹C-Choline PET/CT: an inter- and intra-observer variation study.

ABSTRACT:

Background

Use of ¹¹C-Choline PET/CT is gaining ground in detecting hyperfunctioning parathyroid glands in primary hyperparathyroidism. The purpose of this study was to evaluate the robustness of ¹¹C-Choline PET/CT by assessing intra- and inter-observer agreement to determine whether the method was reader sensitive and therefore should only be performed at highly specialised sites with a high number of cases. PET/CT images of 40 patients diagnosed with primary hyperparathyroidism were anonymised and evaluated three times by three readers: an expert reader and two non-experts (non-experts were experienced in PET/CT imaging, but not in ¹¹C-Choline PET/CT in the setting of primary hyperparathyroidism). Number of hyperfunctioning parathyroid glands, loc

SUBMITTER: Christensen JW 

PROVIDER: S-EPMC8257818 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature