The ratio of single to co-colonization is key to complexity in interacting systems with multiple strains.

ABSTRACT: The high number and diversity of microbial strains circulating in host populations have motivated extensive research on the mechanisms that maintain biodiversity. However, much of this work focuses on strain-specific and cross-immunity interactions. Another less explored mode of pairwise interaction is via altered susceptibilities to co-colonization in hosts already colonized by one strain. Diversity in such interaction coefficients enables strains to create dynamically their niches for growth and persistence, and "engineer" their common environment. How such a network of interactions with others mediates collective coexistence remains puzzling analytically and computationally difficult to simulate. Furthermore, the gradients modulating stability-complexity regimes in such multi-player end

SUBMITTER: Gjini E 

PROVIDER: S-EPMC8258234 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature