Heart Rate Variability in Postoperative Patients with Nonfunctioning Pituitary Adenoma.

ABSTRACT:

Background

Decreased heart rate variability (HRV) has been reported to be associated with cardiac autonomic dysfunction. Hypopituitarism in nonfunctioning pituitary adenoma (NFPA) is often linked to increased cardiovascular mortality. We therefore hypothesized that postoperative NFPA patients with hormone deficiency have an elevated risk of HRV alterations indicating cardiac autonomic dysfunction.

Methods

A total of 22 patients with NFPA were enrolled in the study. Between 3 and 6 months after surgery, a combined pituitary function test (CPFT) was performed, and HRV was measured. The period of sleep before the CPFT was deemed the most stable period, and the hypoglycemic period that occurred during the CPFT was defined as the most unstable period. Changes in HRV parameters in

SUBMITTER: Ha J 

PROVIDER: S-EPMC8258319 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature