Variation in Pyramidal Cell Morphology Across the Human Anterior Temporal Lobe.

ABSTRACT: Pyramidal neurons are the most abundant and characteristic neuronal type in the cerebral cortex and their dendritic spines are the main postsynaptic elements of cortical excitatory synapses. Previous studies have shown that pyramidal cell structure differs across layers, cortical areas, and species. However, within the human cortex, the pyramidal dendritic morphology has been quantified in detail in relatively few cortical areas. In the present work, we performed intracellular injections of Lucifer Yellow at several distances from the temporal pole. We found regional differences in pyramidal cell morphology, which showed large inter-individual variability in most of the morphological variables measured. However, some values remained similar in all cases. The smallest and least complex cell

SUBMITTER: Benavides-Piccione R 

PROVIDER: S-EPMC8258433 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature