Recalibration of the Renal Angina Index for Pediatric Septic Shock.

ABSTRACT:

Introduction

Sepsis-associated acute kidney injury (AKI) is a common diagnosis in children that is associated with poor outcomes. The lack of therapeutic options once present makes early identification of at-risk patients essential. The renal angina index (RAI) has been previously validated to predict severe AKI in heterogeneous populations of critically ill children. The performance of this score specifically in children with septic shock is unknown.

Methods

A secondary analysis of a multicenter, prospective, observational study of 379 children with septic shock to determine the ability of the RAI to predict severe AKI at day 3, and to assess for the potential need for recalibration of the RAI in this unique subset of patients.

Results

At the original cutoff of ≥8, t

SUBMITTER: Stanski NL 

PROVIDER: S-EPMC8258591 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature