Biological sources of variations of tartrate-resistant acid phosphatase 5b in a healthy Japanese population.

ABSTRACT:

Background

Tartrate-resistant acid phosphatase 5b (TRACP5b) is a bone resorption marker that is mainly used in clinical management of osteoporosis. For proper interpretations of test results for serum TRACP5b, we explored their biological sources of variation, esp. age-related changes, and associations with other bone-related markers in healthy Japanese adults.

Methods

During the 2009 East-Southeast Asian multicentre study for determination of reference intervals, 72 major laboratory tests were measured by centralized assays in 3541 well-defined healthy volunteers. The current study included 1980 test results in Japanese subjects for five bone-related markers: TRACP5b, bone alkaline phosphatase, intact parathyroid hormone, calcium and inorganic phosphate. Information on sour

SUBMITTER: Kikuchi W 

PROVIDER: S-EPMC8258717 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature