Association of fluid balance trajectories with clinical outcomes in patients with septic shock: a prospective multicenter cohort study.

ABSTRACT:

Background

Septic shock has a high incidence and mortality rate in Intensive Care Units (ICUs). Earlier intravenous fluid resuscitation can significantly improve outcomes in septic patients but easily leads to fluid overload (FO), which is associated with poor clinical outcomes. A single point value of fluid cannot provide enough fluid information. The aim of this study was to investigate the impact of fluid balance (FB) latent trajectories on clinical outcomes in septic patients.

Methods

Patients were diagnosed with septic shock during the first 48 h, and sequential fluid data for the first 3 days of ICU admission were included. A group-based trajectory model (GBTM) which is designed to identify groups of individuals following similar developmental trajectories was used to

SUBMITTER: Wang MP 

PROVIDER: S-EPMC8258941 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature