European Registry on Helicobacter pylori management: Single-capsule bismuth quadruple therapy is effective in real-world clinical practice.

ABSTRACT:

Background

There has been resurgence in the use of bismuth quadruple therapy (proton pump inhibitor, bismuth, tetracycline and metronidazole) for treating Helicobacter pylori infection thanks to a three-in-one single-capsule formulation.

Objective

To evaluate the effectiveness and safety of the single-capsule bismuth quadruple therapy.

Methods

Data were collected in a multicentre, prospective registry of the clinical practice of gastroenterologists on the management of H. pylori infection, where patients were registered at the Asociación Española de Gastroenterologia REDCap database on an electronic case report form until January 2020. Effectiveness by modified intention-to-treat and per-protocol as well as multivariable analysis were performed. Independent factors ev

SUBMITTER: Nyssen OP 

PROVIDER: S-EPMC8259339 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature