Do Weight trajectories influence diabetes control? A prospective study in Switzerland (CoLaus study).

ABSTRACT:

Objective

Identify anthropometric trajectories among subjects with type 2 diabetes mellitus (T2DM), and associate them with glycaemic control.

Methods

Prospective study including 268 community-dwelling participants with T2DM (34% women, mean age 68.7 ± 8.9 years) followed for 10.7 years (range: 8.8-13.6 years). T2DM control was considered for 1) fasting plasma glucose (FPG) < 7.0 mmol/L, or 2) HbA₁c < 7.0% (53 nmol/mol). Changes in weight or waist and weight variability were considered.

Results

One half (FPG) and one third (HbA₁c) of participants presented with uncontrolled T2DM. Half of the participants presented with obesity and 75% with abdominal obesity. During follow-up, half of the participants maintained their weight, 25% gained > 5 kg, an

SUBMITTER: Ducraux P 

PROVIDER: S-EPMC8259406 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature