Association between Postmortem Kidney Biopsy Findings and Acute Kidney Injury from Patients with SARS-CoV-2 (COVID-19).

ABSTRACT:

Background and objectives

AKI in coronavirus disease 2019 (COVID-19) is associated with higher morbidity and mortality. The objective of this study was to identify the kidney histopathologic characteristics of deceased patients with diagnosis of COVID-19 and evaluate the association between biopsy findings and clinical variables, including AKI severity.

Design, setting, participants, & measurements

Our multicenter, observational study of deceased patients with COVID-19 in three third-level centers in Mexico City evaluated postmortem kidney biopsy by light and electron microscopy analysis in all cases. Descriptive and association statistics were performed between the clinical and histologic variables.

Results

A total of 85 patients were included. Median age was 57 (49-

SUBMITTER: Rivero J 

PROVIDER: S-EPMC8259494 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature