Supplementation of EPA and DHA in pregnant women with type 1 diabetes mellitus.

ABSTRACT:

Background/objective

Lower proportions of n-3 PUFAs have been observed in neonates born to diabetic mothers. We aimed to investigate the association between DHA and EPA supplementation during pregnancy complicated with type 1 diabetes on concentration and proportion of fatty acids in maternal and foetal blood.

Subjects and methods

We conducted a prospective randomized, single-blinded, placebo-controlled trial of 111 eligible pregnant women with type 1 diabetes and presented the results of 84 (intervention arm and control arm comprised 42 participants each) of them who successfully finished the trial in an academic hospital. The initiation of EPA and DHA supplementation or placebo started at randomization visit on gestational week 11-12. Blood samples were taken on the first

SUBMITTER: Ivanisevic M 

PROVIDER: S-EPMC8260041 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature