Design characteristics of comparative effectiveness trials for the relief of symptomatic dyspepsia: A systematic review.

ABSTRACT:

Background

Dyspepsia represents a symptom domain rather than a diagnostic condition and covers a wide range of complex, underlying pathophysiologies that are not well understood. The review explores comparative effectiveness interventions for the treatment of symptomatic dyspepsia along a pragmatic-explanatory continuum. The aim is to identify relevant design characteristics applicable to future upper gastrointestinal comparative effectiveness research employing integrative medicine.

Methods

Medline, CINAHL, Scopus, Cochrane Central Register of Controlled Trials (CENTRAL) and WHO Clinical Trials were systematically searched until January 2019. Included articles were original research with two or more comparative intervention arms for the primary outcome; relief of symptomati

SUBMITTER: Elliott N 

PROVIDER: S-EPMC8260395 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature