Untargeted fecal metabolome analysis in obese dogs after weight loss achieved by feeding a high-fiber-high-protein diet.

ABSTRACT:

Introduction

In humans and companion animals, obesity is accompanied by metabolic derangements. Studies have revealed differences in the composition of the fecal microbiome between obese dogs and those with an ideal body weight.

Objectives

We have previously reported that the fecal microbiome in obese dogs changes after controlled weight reduction, induced by feeding a diet high in fiber and protein. Despite these findings, it is unclear if taxonomic differences infer differences at the functional level between obese dogs and those with an ideal body weight.

Methodology

Untargeted fecal metabolome analysis was performed on dogs with obesity before and after weight loss achieved by feeding a high-fiber-high-protein diet.

Results

Fecal metabolome analysis reveale

SUBMITTER: Bermudez Sanchez S 

PROVIDER: S-EPMC8260550 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature