Optimal medical therapy with or without surgical revascularization and long-term outcomes in ischemic cardiomyopathy.

ABSTRACT:

Objectives

Optimal medical therapy in patients with heart failure and coronary artery disease is associated with improved outcomes. However, whether this association is influenced by the performance of coronary artery bypass grafting is less well established. Thus, the aim of this study was to determine the possible relationship between coronary artery bypass grafting and optimal medical therapy and its effect on the outcomes of patients with ischemic cardiomyopathy.

Methods

The Surgical Treatment for Ischemic Heart Failure trial randomized 1212 patients with coronary artery disease and left ventricular ejection fraction 35% or less to coronary artery bypass grafting with medical therapy or medical therapy alone with a median follow-up over 9.8 years. For the purpose of this

SUBMITTER: Farsky PS 

PROVIDER: S-EPMC8260609 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature