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EASIX for Prediction of Outcome in Hospitalized SARS-CoV-2 Infected Patients.


ABSTRACT:

Background

The coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and has evoked a pandemic that challenges public health-care systems worldwide. Endothelial cell dysfunction plays a key role in pathophysiology, and simple prognosticators may help to optimize allocation of limited resources. Endothelial activation and stress index (EASIX) is a validated predictor of endothelial complications and outcome after allogeneic stem cell transplantation. Aim of this study was to test if EASIX could predict life-threatening complications in patients with COVID-19.

Methods

SARS-CoV-2-positive, hospitalized patients were enrolled onto a prospective non-interventional register study (n=100). Biomarkers were assessed at hospital

SUBMITTER: Luft T 

PROVIDER: S-EPMC8261154 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature