Association Between Visceral Fat and Brain Cortical Thickness in the Elderly: A Neuroimaging Study.

ABSTRACT:

Background

Despite emerging evidence suggesting that visceral fat may play a major role in obesity-induced neurodegeneration, little evidence exists on the association between visceral fat and brain cortical thickness in the elderly.

Purpose

We aimed to examine the association between abdominal fat and brain cortical thickness in a Korean elderly population.

Methods

This cross-sectional study included elderly individuals without dementia (n = 316). Areas of visceral fat and subcutaneous fat (cm²) were estimated from computed tomography scans. Regional cortical thicknesses (mm) were obtained by analyzing brain magnetic resonance images. Given the inverted U-shaped relationship between visceral fat area and global cortical thickness (examined using a g

SUBMITTER: Cho J 

PROVIDER: S-EPMC8261238 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature