Association of Aortic Stiffness and Cognitive Decline: A Systematic Review and Meta-Analysis.

ABSTRACT: Background: Increased aortic stiffness has been found to be associated with cognitive function decline, but the evidence is still under debate. It is of great significance to elucidate the evidence in this debate to help make primary prevention decisions to slow cognitive decline in our routine clinical practice. Methods: Electronic databases of PubMed, EMBASE, and Cochrane Library were systematically searched to identify peer-reviewed articles published in English from January 1, 1986, to March 16, 2020, that reported the association between aortic stiffness and cognitive function. Studies that reported the association between aortic pulse wave velocity (PWV) and cognitive function, cognitive impairment, and dementia were included in the analysis. Results: Thirty-nine

SUBMITTER: Liu Q 

PROVIDER: S-EPMC8261283 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature