Early recognition of necrotizing pneumonia in children based on non-contrast-enhanced computed tomography radiomics signatures.

ABSTRACT:

Background

Necrotizing pneumonia (NP) is an infrequent but severe complication of pneumonia in children. In the early stages of NP, CT imaging shows lung consolidation, which cannot be detected in time. This study aimed to explore the ability of non-contrast-enhanced CT radiomics features to recognize NP in early stage.

Methods

This was a retrospective study, and 250 patients who presented with lung consolidation on initial CT images were included in this study. After a follow-up period of 1-3 weeks, 116 patients developed NP, whose CT or X-ray shows cavitation or liquefied necrosis. Manual segmentation of lesion sites in the initial non-contrast-enhanced CT scans was performed with RadCloud (Huiying Medical Technology Co., Ltd., China), and 1,409 radiomics features were ext

SUBMITTER: Chen X 

PROVIDER: S-EPMC8261593 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature