Disparities by Race and Ethnicity Among Adults Recruited for a Preclinical Alzheimer Disease Trial.

ABSTRACT:

Importance

Underrepresentation of many racial/ethnic groups in Alzheimer disease (AD) clinical trials limits generalizability of results and hinders opportunities to examine potential effect modification of candidate treatments.

Objective

To examine racial and ethnic differences in recruitment methods and trial eligibility in a multisite preclinical AD trial.

Design, setting, and participants

This cross-sectional study analyzed screening data from the Anti-Amyloid in Asymptomatic AD study, collected from April 2014 to December 2017. Participants were categorized into 5 mutually exclusive ethnic/racial groups (ie, Hispanic, Black, White, Asian, and other) using participant self-report. Data were analyzed from May through December 2020 and included 5945 cognitively unim

SUBMITTER: Raman R 

PROVIDER: S-EPMC8261604 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature