Introducing the non-invasive prenatal testing for detection of Down syndrome in China: a cost-effectiveness analysis.

ABSTRACT:

Objective

This study aimed to compare the health economic value of a non-invasive prenatal testing (NIPT) strategy against a second-trimester triple screening (STS) strategy for the detection of Down syndrome based on real-world data from China.

Design

A decision-analytical model was developed to compare the cost-effectiveness of five strategies from a societal perspective. Cost and probability input data were obtained from the real-world surveys and published sources.

Setting

China.

Participants

Women with a singleton pregnancy.

Interventions

The five strategies for screening were: (A) maternal age with STS (no NIPT); (B) STS plus NIPT screening; (C) age-STS plus NIPT screening (the currently referral strategy in China); (D) maternal age with NIPT scree

SUBMITTER: Shang W 

PROVIDER: S-EPMC8261875 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature