Economic Evaluations in National Cancer Institute-Sponsored Network Cancer Clinical Trials.

ABSTRACT:

Objectives

Amid a rapid increase in cancer care costs, we examined the extent to which economic evaluations (EEs) were conducted for new treatments evaluated in clinical trials at SWOG, a large National Cancer Institute-sponsored cancer research network.

Methods

We investigated phase III cancer treatment clinical trials activated from 1980 onward with primary articles reporting the protocol-designated endpoints published in scientific journals by 2017. Using PubMed, Web of Science, and EconLit, we searched for EEs using trial name, cancer type, information on the comparison arms, and refined keywords for EE designs. We reported the overall proportion of trials with associated EEs and trends of this proportion over time. We synthesized and analyzed information on funding sour

SUBMITTER: Nghiem VT 

PROVIDER: S-EPMC8262264 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature